1. Disposable Cellbagú: Cells and media are contained inside a single-use bag. These radiation sterilized Cellbags include filters, tubes and all necessary fittings. They are delivered ready for use. Cellbags are available in several sizes for 0.1 to 500 liters of culture volume.

2. Rocker: The rocker unit has optimized devices designed to inflate and rock the Cellbag for oxygen transfer and mixing. These rugged machines are designed to give years of reliable service. Options include CO₂ control, DO monitoring, temperature control, weight control, pH control, and data acquisition. Units can be used in an incubator or standalone.

The Wave Bioreactor is the ideal device for cell culture. Culture medium and cells only contact a presterile, disposable chamber called a Cellbag that is placed on a special rocking platform. The rocking motion of this platform induces waves in the culture fluid. These waves provide mixing and oxygen transfer, resulting in a perfect environment for cell growth that can easily support over 10 x 10⁶ cells/ml. The bioreactor requires no cleaning or sterilization, providing the ultimate ease in operation and protection against cross-contamination.

Scalable to 500 Liters
The Wave Bioreactor is available in sizes up to 500 liter culture volume:

• SYSTEM2/10 for 100ml to 5 liters
• SYSTEM20/50 for 1 to 25 liters
• SYSTEM200 for 10 to 100 liters
• SYSTEM500/1000 for 50 to 500 liters

Disposable Bioreactor Chamber
Culture only contacts a presterile plastic disposable cultivation chamber. No cross-contamination, cleaning, sterilization or other validation headaches.

Completely Closed System
Ideal for virus or vaccine production, high containment applications, and cGMP operations. No biosafety cabinet is needed, even for additions and sampling.

Versatile
Multiple instrument configurations specifically designed for suspension, microcarrier, batch, fed-batch or perfusion culture. Use pneumatic unit inside an incubator or benchtop models with integral temperature control.

Suitable for cGMP Operations
Used in the GMP production of human therapeutics. Closed system is easy to validate. All Cellbag contact materials conform to USP Class VI and ISO 10993.

Perfusion Culture Option
Patented internal perfusion filters enable perfusion of media for high-density cell culture. No pumparound or external cell separator needed.

Easy to Operate
No complex piping or sterilization sequences. Simply place a new presterile Cellbag on the rocker; fill with media, and add your cells.