SELECT A CASE STUDY Monoclonal Antibody Production GMP Inoculum Propagation Insect Cell Cultivation Gene Therapy Perfusion E. Coli Protein Expression Plant Cell Culture Growing Pathogens Cell Therapy Adenovirus Production Adherent Cell Apps

Adenovirus Production

HEK293 cells expanded from 1L to 10L in System20/50 Continuous perfusion enabled at 10L Culture perfused until cells reach density of 10-20x106 cells/ml 10L culture then transferred to System200 and 90L fresh media is added, cells are infected with Adenovirus Result is 100,000 vp/cell “…are planning to use the Wave system in the production process for our next product candidate in Phase 2”